Table 1. Top ten two-way interactions found in the analysis of the ever smokers.

SNP combination	OR (95% CI)	P-value
rs11892031 [A/A] × GSTM1 null	1.48 (1.25–1.76)	0.0024
rs8102137 [C/T, T/T] × GSTM1 null	1.51 (1.25–1.82)	0.0040
rs710521 [A/A, A/G] × GSTM1 null	1.46 (1.22–1.73)	0.0062
rs710521 [A/A, A/G] × GSTM1 present	0.69 (0.58–0.83)	0.0105
rs9642880 [G/G, G/T] × GSTM1 present	0.69 (0.57–0.82)	0.0113
rs11892031 [A/A, A/C] × GSTM1 present	0.70 (0.59–0.84)	0.0185
rs11892031 [A/A, A/C] × GSTM1 null	1.42 (1.19–1.69)	0.0204
rs1014971 [C/C, C/T] × GSTM1 present	0.71 (0.60–0.84)	0.0303
rs1495741 [A/A, A/G] × GSTM1 null	1.40 (1.18–1.66)	0.0398
rs1014971 [C/C, C/T] × GSTM1 null	1.38 (1.16–1.64)	0.0703

The top ten of the 288 possible two-way interactions comprised of the six SNPs and GSTM1 as well as their odds ratios (OR) with 95% confidence intervals (CI) are listed in order of their p-values, where the p-values were adjusted for multiple comparisons by the Bonferroni correction.