Table 2. Top ten two-way interactions found in the analysis of the non-smokers.
SNP combination | OR (95% CI) | P-value |
rs9642880 [G/T, T/T] × rs1014971 [C/C] | 1.91 (1.44–2.51) | 0.0015 |
rs9642880 [G/G, G/T] × rs1014971 [C/T, T/T] | 0.56 (0.43–0.74) | 0.0112 |
rs710521 [A/A, A/G] × rs1014971 [C/C] | 1.68 (1.28–2.20) | 0.0458 |
rs1014971 [C/C] × rs1495741 [A/A, A/G] | 1.66 (1.27–2.16) | 0.0524 |
rs1014971 [C/C] × rs11892031 [A/A, A/C] | 1.65 (1.27–2.16) | 0.0564 |
rs1014971 [C/T, T/T] × rs8102137 [C/C, C/T] | 0.61 (0.46–0.79) | 0.0640 |
rs1014971 [C/C] × rs11892031 [A/A] | 1.65 (1.26–2.15) | 0.0761 |
rs9642880 [T/T] × rs710521 [A/A, A/G] | 1.75 (1.29–2.37) | 0.0827 |
rs1014971 [C/T, T/T] × rs1495741 [A/A, A/G] | 0.62 (0.47–0.81) | 0.1051 |
rs1014971 [C/C] × GSTM1 null | 1.73 (1.28–2.35) | 0.1111 |
The top ten of the 288 possible two-way interactions comprised of the six SNPs and GSTM1 as well as their odds ratios (OR) with 95% confidence intervals (CI) are listed in order of their p-values, where the p-values were adjusted for multiple comparisons by the Bonferroni correction.