Table 6. Population attributable risks and odds ratios due to genetic factors.

	Present study		Published
Genetic Factors	PAR	OR	PAR	OR
All	–	–	30% [47], [51]	1.04–1.81 [1], [9], [31], [48]
GSTM1	13%a	1.28	14–26% [47], [48], [54], [55]	1.28–1.70 [47], [48], [54], [55]
NAT2	1%b	1.02b	8.2%c [54]	1.04–1.43 [47], [48], [54], [56]
“wimp” SNPs	33%d	1.02–1.34e	–	1.11–1.81 [1], [9], [32]
Top 3-way interaction	16%	1.48	–	–

Population attributable risks (PARs) and odds ratios (ORs) were calculated from the data of the present study and summarized from previously published studies for different genetic factors. Numbers in brackets refer to the publications in which the PARs and ORs were published.

^aAdjusted for age, gender, smoking habits, all measured SNPs and study site; crude PAR/OR: 16%/1.39; adjusted for age and gender: 16%/1.37; adjusted for all measured SNPs: 15%/1.36.

^bAdjusted for age, gender, smoking habits, all measured SNPs and study site; crude PAR/OR: 5%/1.09; adjusted for age and gender: 3%/1.05; adjusted for all measured SNPs: 5%/1.10.

^cData from Moore et al. [48] and Garcia-Closas et al.[47] result in PARs of 2–18%.

^dCombined PAR, individual SNP OR and PAR adjusted for age, gender, smoking habits and all measured SNPs.

^eRange of individual SNP OR adjusted for age, gender, smoking habits, all measured SNPs and study site depending on the mode of inheritance.