Figure 4. TEA sensitivity of the outward current as a function of postnatal day.
(A) The reduction of the outward current to 20 mM TEA was assayed with the protocol in figure 7. (B) Comparison of the differences in pharmacology for the total non-inactivating outward current, between early (P0) and late (P7–P15) SN DA neurons. Experimental protocol as explained in figure legends 5 & 6. Control conductance (Left white bar, G(Control, P0) nS, n = 10). At P0 the currents are insensitive to 20 mM TEA (Left Black bar, G(TEA, P0)
nS, n = 4), 1
m CbTx (Left hatch bar, G(CbTx, P0)
nS, n = 3) and 1
m IbTx (left criss-cross bar, G(IbTx, P0)
nS, n = 2). Average control conductance pooled from P7 to P15 (Right white bar, G(Control, P7–P15)
nS, n = 23). Effect of 20 mM TEA on the conductance from P7–P15 (Right black bar (G(TEA, P7–P15)
nS, n = 10). Effects of 1
m CbTx (Right hatch bar G(CbTx, P7–P15)
nS, n = 3) and 1
M IbTx (Right criss-cross bar, G(IbTx)
nS, n = 2) on the conductance, data pooled from P7 to P15.