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. 2012 Dec 20;7(12):e52465. doi: 10.1371/journal.pone.0052465

Figure 2. Gastric cancer cell derived exosomes induces the expression of CAF markers in hucMSCs.

Figure 2

A.Quantitative analyses of the FAP, IL-6 and α-SMA mRNA expression in hucMSCs. HucMSCs were treated with various concentrations of SGC7901 exosomes or GES-1 exosomes for 36 hours. B. Quantitative analyses of the FAP, IL-6 and N-Cadherin expression in hucMSCs. HucMSCs were treated with various concentrations of SGC7901 exosomes or GES-1 exosomes for 14 days. C. Western blotting analyses of the FAP, α-SMA, N-Cadherin and Vimentin protein expression in hucMSCs treated with SGC7901 exosomes (800 µg/ml) for different times. (a–d) Density analysis of Western blotting bands. *P<0.05 and # P<0.01, compared to the relative control group (n = 3).