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. 2012 Dec 20;7(12):e52389. doi: 10.1371/journal.pone.0052389

Figure 5. Immunohistochemical staining of abnormal tau.

Figure 5

(A) An AT8 immunoreaction was observed only in spinal cord, medulla oblongata and pons of a mouse with a low AT8/HT7 ratio. (B) AT8-positive cells were seen in spinal cord, medulla oblongata, pons, midbrain, hypothalamus and cerebral cortex of a mouse with a high AT8/HT7 ratio. Each insert shows the cerebral cortex of the mouse brain.