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. 2012 Dec 20;7(12):e52349. doi: 10.1371/journal.pone.0052349

Table 3. Disease severity and adjunctive treatment by regimen.

Clinical Characteristic Colistin+Carbapenem (n = 21) Other Regimens (n = 16) p-value
Median APACHE II score (range) 19 (10–29) 20 (8–28) 0.93
Co-pathogen present, no. (%) 9 (43%) 9 (56%) 0.52
Intensive care unit, no. (%) 20 (95%) 20 (100%) 1.00
Mechanical ventilation, no. (%) 20 (95%) 20 (100%) 1.00
Ventilator-associated pneumonia, no. (%) 17 (81%) 15 (94%) 0.36
Associated infection, no. (%) 3 (14%) 5 (31%) 0.25
Inhaled colistin, no. (%)* 10 (48%) 5 (31%) 0.50
Median duration of treatment, days (range) 15 (5–44) 7.5 (3–52) 0.09
*

Only patients with XDR-Ab pneumonia received inhaled colistin; all patients receiving inhaled colistin were on concomitant systemic colistin therapy.