Table 3. Disease severity and adjunctive treatment by regimen.
Clinical Characteristic | Colistin+Carbapenem (n = 21) | Other Regimens (n = 16) | p-value |
Median APACHE II score (range) | 19 (10–29) | 20 (8–28) | 0.93 |
Co-pathogen present, no. (%) | 9 (43%) | 9 (56%) | 0.52 |
Intensive care unit, no. (%) | 20 (95%) | 20 (100%) | 1.00 |
Mechanical ventilation, no. (%) | 20 (95%) | 20 (100%) | 1.00 |
Ventilator-associated pneumonia, no. (%) | 17 (81%) | 15 (94%) | 0.36 |
Associated infection, no. (%) | 3 (14%) | 5 (31%) | 0.25 |
Inhaled colistin, no. (%)* | 10 (48%) | 5 (31%) | 0.50 |
Median duration of treatment, days (range) | 15 (5–44) | 7.5 (3–52) | 0.09 |
Only patients with XDR-Ab pneumonia received inhaled colistin; all patients receiving inhaled colistin were on concomitant systemic colistin therapy.