Table 1. The effects of treatment with 10 µM KB-R7943 or 10 µM MDL28170 on the percentage of calpain membrane-positive cells in the hearts subjected to the 3-min Ca2+ depletion and 2-min Ca2+ repletion.
control | MDL+C | KBR+C | CaD3 | MDL+CaD3 | KBR+CaD3 | |
% μ-calpain positive cells | 0 | 0 | 0 | 23.2±3.1## | 7.6±1.1** | 3.5±0.4** |
% m-calpain positive cells | 0 | 0 | 0 | 3.1±0.4## | 2.2±0.5 | 0.8±0.1** |
The data are documented as the mean±SEM, n = 4.
P<0.01 vs. the control,
P<0.01 vs. the corresponding group without the drug. KBR+C, KB-R7943 control; MDL+C, MDL28170 control; CaD3, 3-min Ca2+ depletion group; MDL, MDL28170; and KBR, KB-R7943.