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. 2012 Dec 20;7(12):e52643. doi: 10.1371/journal.pone.0052643

Table 3. Odds ratios (and 95% confidence intervals) of tertiles of baseline serum carotenoid concentration on osteoporosis in post-menopausal Japanese female subjects.

Serum carotenoids N Mean and range of serum carotenoid (µmol/L) Case Model 1 Model 2
OR 95% CI P for trend OR 95% CI P for trend
Lutein Lowest (T1) 60 0.38 (0.23–0.47) 6 1.00 1.00
Middle (T2) 66 0.56 (0.49–0.63) 6 0.69 (0.19–2.51) 0.47 (0.10–2.13)
Highest (T3) 61 0.78 (0.65–2.11) 5 0.53 (0.14–2.05) 0.356 0.54 (0.11–2.60) 0.433
Lycopene Lowest (T1) 59 0.23 (0.07–0.32) 7 1.00 1.00
Middle (T2) 61 0.38 (0.34–0.45) 4 0.71 (0.17–2.97) 0.57 (0.11–2.81)
Highest (T3) 67 0.62 (0.47–1.06) 6 0.91 (0.25–3.37) 0.890 0.58 (0.14–2.51) 0.481
α-Carotene Lowest (T1) 67 0.13 (0.07–0.17) 7 1.00 1.00
Middle (T2) 56 0.21 (0.19–0.22) 5 0.80 (0.22–2.94) 0.64 (0.13–3.09)
Highest (T3) 64 0.38 (0.24–2.74) 5 0.76 (0.20–2.94) 0.694 0.71 (0.14–3.68) 0.733
β-Carotene Lowest (T1) 61 0.69 (0.35–0.91) 9 1.00 1.00
Middle (T2) 64 1.17 (0.95–1.42) 4 0.32 (0.08–1.28) 0.26 (0.05–1.24)
Highest (T3) 62 1.91 (1.43–3.37) 4 0.30 (0.08–1.13) 0.071 0.24 (0.05–1.21) 0.082
β-Cryptoxanthin Lowest (T1) 62 0.81 (0.24–1.41) 9 1.00 1.00
Middle (T2) 63 1.87 (1.43–2.39) 7 0.83 (0.24–2.90) 0.63 (0.16–2.42)
Highest (T3) 62 3.60 (2.41–10.53) 1 0.08 (0.01–0.75) 0.021 0.07 (0.01–0.88) 0.034
Zeaxanthin Lowest (T1) 56 0.15 (0.09–0.18) 8 1.00 1.00
Middle (T2) 64 0.20 (0.19–0.21) 5 0.50 (0.14–1.84) 0.50 (0.12–2.04)
Highest (T3) 67 0.26 (0.23–0.37) 4 0.36 (0.09–1.38) 0.130 0.35 (0.08–1.52) 0.149

Model 1: Age, weight, height, years since menopause, current tobacco use, regular alcohol intake, exercise habits, supplement use, and total energy intake were adjusted.

Model 2: Intakes of calcium, magnesium, potassium, and vitamins D, C, and E were further adjusted.