Table 3. Odds ratios (and 95% confidence intervals) of tertiles of baseline serum carotenoid concentration on osteoporosis in post-menopausal Japanese female subjects.
Serum carotenoids | N | Mean and range of serum carotenoid (µmol/L) | Case | Model 1 | Model 2 | ||||||
OR | 95% CI | P for trend | OR | 95% CI | P for trend | ||||||
Lutein | Lowest (T1) | 60 | 0.38 | (0.23–0.47) | 6 | 1.00 | 1.00 | ||||
Middle (T2) | 66 | 0.56 | (0.49–0.63) | 6 | 0.69 | (0.19–2.51) | 0.47 | (0.10–2.13) | |||
Highest (T3) | 61 | 0.78 | (0.65–2.11) | 5 | 0.53 | (0.14–2.05) | 0.356 | 0.54 | (0.11–2.60) | 0.433 | |
Lycopene | Lowest (T1) | 59 | 0.23 | (0.07–0.32) | 7 | 1.00 | 1.00 | ||||
Middle (T2) | 61 | 0.38 | (0.34–0.45) | 4 | 0.71 | (0.17–2.97) | 0.57 | (0.11–2.81) | |||
Highest (T3) | 67 | 0.62 | (0.47–1.06) | 6 | 0.91 | (0.25–3.37) | 0.890 | 0.58 | (0.14–2.51) | 0.481 | |
α-Carotene | Lowest (T1) | 67 | 0.13 | (0.07–0.17) | 7 | 1.00 | 1.00 | ||||
Middle (T2) | 56 | 0.21 | (0.19–0.22) | 5 | 0.80 | (0.22–2.94) | 0.64 | (0.13–3.09) | |||
Highest (T3) | 64 | 0.38 | (0.24–2.74) | 5 | 0.76 | (0.20–2.94) | 0.694 | 0.71 | (0.14–3.68) | 0.733 | |
β-Carotene | Lowest (T1) | 61 | 0.69 | (0.35–0.91) | 9 | 1.00 | 1.00 | ||||
Middle (T2) | 64 | 1.17 | (0.95–1.42) | 4 | 0.32 | (0.08–1.28) | 0.26 | (0.05–1.24) | |||
Highest (T3) | 62 | 1.91 | (1.43–3.37) | 4 | 0.30 | (0.08–1.13) | 0.071 | 0.24 | (0.05–1.21) | 0.082 | |
β-Cryptoxanthin | Lowest (T1) | 62 | 0.81 | (0.24–1.41) | 9 | 1.00 | 1.00 | ||||
Middle (T2) | 63 | 1.87 | (1.43–2.39) | 7 | 0.83 | (0.24–2.90) | 0.63 | (0.16–2.42) | |||
Highest (T3) | 62 | 3.60 | (2.41–10.53) | 1 | 0.08 | (0.01–0.75) | 0.021 | 0.07 | (0.01–0.88) | 0.034 | |
Zeaxanthin | Lowest (T1) | 56 | 0.15 | (0.09–0.18) | 8 | 1.00 | 1.00 | ||||
Middle (T2) | 64 | 0.20 | (0.19–0.21) | 5 | 0.50 | (0.14–1.84) | 0.50 | (0.12–2.04) | |||
Highest (T3) | 67 | 0.26 | (0.23–0.37) | 4 | 0.36 | (0.09–1.38) | 0.130 | 0.35 | (0.08–1.52) | 0.149 |
Model 1: Age, weight, height, years since menopause, current tobacco use, regular alcohol intake, exercise habits, supplement use, and total energy intake were adjusted.
Model 2: Intakes of calcium, magnesium, potassium, and vitamins D, C, and E were further adjusted.