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. 2012 Dec 20;7(12):e52643. doi: 10.1371/journal.pone.0052643

Table 4. Odds ratios (and 95% confidence intervals) of tertiles of baseline serum carotenoid concentration on osteopenia and/or osteoprosis in post-menopausal Japanese female subjects.

Serum carotenoids n Mean and range of serum carotenoid (µmol/L) Case Model 1 Model 2
OR 95% CI P for trend OR 95% CI P for trend
Lutein Lowest (T1) 47 0.39 (0.28–0.47) 8 1.00 1.00
Middle (T2) 45 0.55 (0.49–0.62) 9 1.48 (0.46–4.68) 1.50 (0.45–5.01)
Highest (T3) 48 0.74 (0.63–1.14) 10 1.29 (0.41–4.08) 0.676 1.62 (0.47–5.56) 0.445
Lycopene Lowest (T1) 48 0.24 (0.07–0.34) 7 1.00 1.00
Middle (T2) 46 0.40 (0.35–0.46) 10 1.61 (0.52–5.00) 2.04 (0.61–6.83)
Highest (T3) 46 0.66 (0.50–1.06) 10 1.54 (0.46–5.13) 0.481 1.57 (0.42–5.90) 0.480
α-Carotene Lowest (T1) 46 0.13 (0.07–0.17) 8 1.00 1.00
Middle (T2) 46 0.21 (0.19–0.24) 9 1.18 (0.39–3.54) 1.55 (0.46–5.18)
Highest (T3) 48 0.39 (0.26–2.75) 10 0.89 (0.29–2.73) 0.806 0.97 (0.28–3.31) 0.889
β-Carotene Lowest (T1) 47 0.70 (0.35–0.97) 9 1.00 1.00
Middle (T2) 47 1.23 (0.99–1.45) 10 0.78 (0.26–2.36) 0.87 (0.28–2.73)
Highest (T3) 46 1.94 (1.50–3.36) 8 0.56 (0.18–1.76) 0.324 0.58 (0.18–1.91) 0.378
β-Cryptoxanthin Lowest (T1) 46 0.85 (0.24–1.45) 14 1.00 1.00
Middle (T2) 47 1.95 (1.50–2.44) 6 0.22 (0.07–0.76) 0.18 (0.05–0.67)
Highest (T3) 47 3.78 (2.47–10.51) 7 0.29 (0.09–0.96) 0.037 0.28 (0.08–0.99) 0.035
Zeaxanthin Lowest (T1) 41 0.15 (0.11–0.18) 7 1.00 1.00
Middle (T2) 50 0.20 (0.19–0.21) 11 1.40 (0.44–4.42) 1.52 (0.46–4.99)
Highest (T3) 49 0.26 (0.23–0.37) 9 1.28 (0.40–4.14) 0.697 1.42 (0.41–4.91) 0.593

Model 1: Age, weight, height, years since menopause, current tobacco use, regular alcohol intake, exercise habits, supplement use, and total energy intake were adjusted.

Model 2: Intakes of calcium, magnesium, potassium, and vitamins D, C, and E were further adjusted.