Table 4. Odds ratios (and 95% confidence intervals) of tertiles of baseline serum carotenoid concentration on osteopenia and/or osteoprosis in post-menopausal Japanese female subjects.
Serum carotenoids | n | Mean and range of serum carotenoid (µmol/L) | Case | Model 1 | Model 2 | ||||||
OR | 95% CI | P for trend | OR | 95% CI | P for trend | ||||||
Lutein | Lowest (T1) | 47 | 0.39 | (0.28–0.47) | 8 | 1.00 | 1.00 | ||||
Middle (T2) | 45 | 0.55 | (0.49–0.62) | 9 | 1.48 | (0.46–4.68) | 1.50 | (0.45–5.01) | |||
Highest (T3) | 48 | 0.74 | (0.63–1.14) | 10 | 1.29 | (0.41–4.08) | 0.676 | 1.62 | (0.47–5.56) | 0.445 | |
Lycopene | Lowest (T1) | 48 | 0.24 | (0.07–0.34) | 7 | 1.00 | 1.00 | ||||
Middle (T2) | 46 | 0.40 | (0.35–0.46) | 10 | 1.61 | (0.52–5.00) | 2.04 | (0.61–6.83) | |||
Highest (T3) | 46 | 0.66 | (0.50–1.06) | 10 | 1.54 | (0.46–5.13) | 0.481 | 1.57 | (0.42–5.90) | 0.480 | |
α-Carotene | Lowest (T1) | 46 | 0.13 | (0.07–0.17) | 8 | 1.00 | 1.00 | ||||
Middle (T2) | 46 | 0.21 | (0.19–0.24) | 9 | 1.18 | (0.39–3.54) | 1.55 | (0.46–5.18) | |||
Highest (T3) | 48 | 0.39 | (0.26–2.75) | 10 | 0.89 | (0.29–2.73) | 0.806 | 0.97 | (0.28–3.31) | 0.889 | |
β-Carotene | Lowest (T1) | 47 | 0.70 | (0.35–0.97) | 9 | 1.00 | 1.00 | ||||
Middle (T2) | 47 | 1.23 | (0.99–1.45) | 10 | 0.78 | (0.26–2.36) | 0.87 | (0.28–2.73) | |||
Highest (T3) | 46 | 1.94 | (1.50–3.36) | 8 | 0.56 | (0.18–1.76) | 0.324 | 0.58 | (0.18–1.91) | 0.378 | |
β-Cryptoxanthin | Lowest (T1) | 46 | 0.85 | (0.24–1.45) | 14 | 1.00 | 1.00 | ||||
Middle (T2) | 47 | 1.95 | (1.50–2.44) | 6 | 0.22 | (0.07–0.76) | 0.18 | (0.05–0.67) | |||
Highest (T3) | 47 | 3.78 | (2.47–10.51) | 7 | 0.29 | (0.09–0.96) | 0.037 | 0.28 | (0.08–0.99) | 0.035 | |
Zeaxanthin | Lowest (T1) | 41 | 0.15 | (0.11–0.18) | 7 | 1.00 | 1.00 | ||||
Middle (T2) | 50 | 0.20 | (0.19–0.21) | 11 | 1.40 | (0.44–4.42) | 1.52 | (0.46–4.99) | |||
Highest (T3) | 49 | 0.26 | (0.23–0.37) | 9 | 1.28 | (0.40–4.14) | 0.697 | 1.42 | (0.41–4.91) | 0.593 |
Model 1: Age, weight, height, years since menopause, current tobacco use, regular alcohol intake, exercise habits, supplement use, and total energy intake were adjusted.
Model 2: Intakes of calcium, magnesium, potassium, and vitamins D, C, and E were further adjusted.