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. 2012 Dec 20;7(12):e52693. doi: 10.1371/journal.pone.0052693

Table 1. Pharmacological Profile of MN10021.

Mediator/Function* MN10021 MN20050
IC50 (µM)
TNF-α 6.2 NE
IL-1β 17 NE
IL-6 NE NE
GM-CSF 8 NE
LTB4 6.2 NE
PAF 12.5 NE
TF 12.5 NE
Chemotaxis 0.25 NE
Adhesion NE NE
Platelet Aggregation 5 NE

NE  =  No Effect.

*

Methods used described in Methods S1.