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. 2012 Dec 20;7(12):e52693. doi: 10.1371/journal.pone.0052693

Table 2. Potency of MN10021 in Mouse Peritonitis Model of Inflammation.

Agent Maximum Inhibition (%) Dose Achieving Maximum Inhibition (µg/nmoles) IC50 (µg/nmoles)
Dexamethasone 75 80/204 ND
Acetaminophen 95 1000/6614 20/132
Diclofenac 90 100/314 5/16
MN10021 70 4/1 0.4/0.1
MN20050 NE NA NA

ND  =  Not Determined.

NE  =  No Effect.

NA  =  Not Applicable.