Table 1. Molecules of interest up-regulated in spheres compared to adherent cells.
| Symbol | Name | ANOVA P-value1 | Fold Change (Adherent to Passage5) | Location | Functional Description and/or Biological/Tumour Function |
| CEACAM6 | carcinoembryonic antigen- related cell adhesion molecule 6 | 1.2E-05 | 5.0E08 | Plasma Membrane | differentiation, cell adhesion, apoptosis, metastasis |
| CEACAM5 | Carcinoembryonic antigen- related cell adhesion molecule 5 | 1.02E-02 | 2.17E08 | Plasma Membrane | differentiation, cell adhesion, apoptosis |
| LGALS3 | galectin-3 | 3.72E-04 | 2.71 | Plasma Membrane, Cytoplasm | cell-cell and cell-matrix interactions, metastasis, anoikis resistance |
| LGALS1 | galectin-1 | 9.71E-03 | 1.90 | Plasma Membrane, Cytoplasm | migration, apoptosis, proliferation, angiogenesis |
| MUC1 | Mucin 1, cell surface associated | 4.53E-07 | 3.56E08 | Plasma Membrane | glycoprotein, oncoprotein role as described in discussion |
| MUC5/MUC5AC | Mucin-5 subtype AC, tracheobronchial | 3.66E-07 | 2.84E08 | Extracellular Space | components of the mucus matrix forming family of mucins |
| MUC5/MUC5B | Mucin-5 subtype B, tracheobronchial | 1.42E-07 | 4.62E08 | Extracellular Space | components of the mucus matrix forming family of mucins |
1) ANOVA p-values comparing adherent, passage2 spheres and passage 5 spheres.