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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: J Membr Biol. 2012 Jul 15;245(7):369–380. doi: 10.1007/s00232-012-9459-x

Fig. 3.

Fig. 3

Cx37-C61,65A does not form hemichannels able to mediate dye uptake. A The percent of cells positive for NBD-M-TMA uptake and negative for rhodamine dextran was compared to determine hemichannel function. In cells induced to express Cx37-WT, dye uptake was significantly more frequent (*p < 0.001) than in noninduced cells or cells induced to express Cx37-C61,65A. B Representative images of DIC (arrows indicate isolated cells or cell clusters), NBD-M-TMA and rhodamine dextran fields for iRin37 induced (a–c) and noninduced (d–f), iRin37-C61,65A 1C3 induced (g–i) and noninduced (j–l). Scale bar = 20 μm, applies to all images