Table 1.
Name | Species | Tasks | Relevant References |
---|---|---|---|
CREB-C/EBP Pathway | |||
CREB | Aplysia | Synaptic facilitation | 24 |
Drosophila | Conditioned odor avoidance | 25 | |
Downstream | Rodent | Fear potentiated startle, water maze | 26,27 |
C/EBP | |||
Aplysia | Synaptic Facilitation | 29 | |
Rodent | MWM | 30 | |
IGF-II | Rodent | IA, CFC, Extinction | 36,89 |
Upstream | |||
MAPK | 31 | ||
PKA | 31 | ||
cAMP | 31 | ||
Calcineurin | Aplysia | Tail-shock sensitization | 34 |
Rodent | nOR, MWM, radial arm maze | 33 | |
PDE4 | Rodent | CFC | 35 |
Synaptic Remodeling | |||
NMDA | |||
Rodent | nOR, AFC, CFC, Extinction, MWM | 39,47 | |
working memory | 40 | ||
D-Cycloserine | Human | FC (cued fear conditioning) | 46 |
AMPA | |||
Ampakines | Rodent | AFC | 52 |
NHP | Delayed-non-match-to-Sample | 52 | |
Human | Delayed Recall | 52 | |
PKMzeta | Rodent | Conditioned Taste Aversion | 50 |
Arc | Rodent | IA | 36,56 |
CNF1 | Rodent | MWM, AFC | 58 |
NCAM | Rodent | MWM, AFC | 59 |
Neuromodulation | |||
Dopamine | Rodent | IA, nOR, Sptial working memory | 66,67 |
NHP | Delayed-non-match-to-sample | 64 | |
Glucocorticoids | |||
Corticosteroid | Rodents | IA, nOR | 69,72 |
Humans | Cued-fear conditioning | 69 | |
Noradrenaline | Rodents | AFC, IA | 73 |
Amphetamines | |||
Methylphenidate | Humans | Delayed Recall, Spatial working memory, Sustained Attention | 10,75,76 |
Acetylcholine | Rodent | MWM, Radial Arm Maze | 77 |
Donepezil | Human | cognitive scales and examinations | 78 |
Endogenous | |||
Glucose | Rodent | IA | 84 |
Human | Verbal Episodic Memory | 83 | |
Insulin | Rodent | Radial Arm Maze | 85 |
Human | Delayed score recall | 86,87 | |
Behavioral | |||
Reconsolidation | Rodent | IA, AFC, CFC | 28,98,99,100 |
Exercise | Rodent | MWM, IA, nOR | 94 |