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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Glia. 2012 Oct 1;61(2):129–139. doi: 10.1002/glia.22422

Figure 4. The effects of the A1R antagonist CPT on cortical slow oscillations are potentiated by sleep loss through an astrocytic SNARE sensitive pathway.

Figure 4

Local field potential (LFP) recordings were made in the somatosensory cortex of either WT or dnSNARE mice. Application of CPT produced an increase in power of slow oscillations (0.4–1Hz) in WT but not dnSNARE mice, and this increase was potentiated by sleep deprivation (FFT of 27s spectral segments, normalized to baseline). Inset, Traces show typical LFP recordings during baseline or following CPT (30s recording at time =22min). Scale bar, 2.5mN, 5s. Adapted from Schmitt et al 2012.