Skip to main content
. 2012 Sep 17;97(1):44–54. doi: 10.1093/cvr/cvs294

Figure 1.

Figure 1

The expression of transgene proteins in the heart. (A) Immunoblots showing the expression of transgenic MYOZ2WT, MYOZ2S48P, and MYOZ2I246M and endogenous MYOZ2 (Endo-MYOZ2) proteins in the heart. Anti-Flag antibody detected transgene MYOZ2 only while a pan specific anti-MYOZ2 antibody detects the endogenous as well as Flag-tagged transgene MYOZ2 in non-transgenic (NTG) and transgenic mice. (B) Immunoblots showing the expression of transgenic MYOZ2WT and MYOZ2I246M in the background of the Myoz2 hemizygous genotype (Myoz2+/−). (C) Quantitative presentation of MYOZ2WT, MYOZ2S48P, and MYOZ2I246M levels as percentages of the total MYOZ2 in the heart in each line of transgenic mice (n = 3–6 mice per line).