Table 2.
Sperm parameters, HPV DNA detection and FISH for HPV observed in testicular cancer patients 1 month after orchiectomy (T0) and after 12 months (T12) from the end of any treatment.
| Groups | Ejaculate volume (mL) | Sperm concentration (million/mL) | Sperm count (million) | Progressive motility (%) | Normal morphology (%) | Positive PCR (%) | FISH on sperm (%) |
|---|---|---|---|---|---|---|---|
| T0 | |||||||
| S (n = 46) | 2.9 ± 1.3 | 19.4 ± 14.4 | 54.6 ± 45.2 | 30.9 ± 14.1 | 19.8 ± 9.5 | 5 (11.1) | 22.4 ± 8.3 |
| R (n = 55) | 3.2 ± 1.5 | 20.7 ± 19.7 | 67.1 ± 55.7 | 33.7 ± 17.6 | 17.9 ± 9.2 | 4 (7.2) | 24.0 ± 3.7 |
| C (n =54) | 3.1 ± 1.1 | 19.4 ± 15.2 | 62.7 ± 60.2 | 29.1 ± 12.9 | 17.9 ± 9.3 | 6 (10.9) | 25.3 ± 3.8 |
| Total (n = 155) | 3.1 ± 1.3 | 19.8 ± 16.6 | 61.9 ± 45.5 | 31.2 ± 15.1 | 18.5 ± 9.3 | 15 (9.7) | 24.0 ± 5.4 |
| T12 | |||||||
| S (n = 42) | 3.1 ± 1.5 | 35.5 ± 25.7* | 94.2 ± 93.5* | 43.7 ± 18.2* | 18.6 ± 10.1 | 4 (7.7) | 24.9 ± 3.7 |
| R (n = 54) | 3.1 ± 1.7 | 23.8 ± 20.6 | 69.9 ± 58.7 | 30.8 ± 15.3# | 18.0 ± 13.7 | 16 (30.8)*, # | 28.7 ± 6.0 |
| C (n = 53) | 3.3 ± 1.5 | 11.1 ± 9.9*, ## | 24.4 ± 17.4*, ## | 20.8 ± 14.2*, ## | 17.1 ± 11.2 | 32 (61.5)**, ## | 39.6 ± 8.2*, # |
| Total (n = 149) | 3.2 ± 1.5 | 22.6 ± 20.6 | 61.3 ± 50.5 | 30.7 ± 18.5 | 17.8 ± 11.5 | 52 (34.9)** | 29.4 ±6.9 |
Data are shown as total and subgrouping patients in: S group = patients who underwent surveillance, R group = patients who underwent radiotherapy, and C group = patients who underwent chemotherapy followed or not by radiotherapy.
*
p < 0.05 vs. T0.
**
p < 0.01 vs. T0.
#
p < 0.05 vs. S.
##
p < 0.01 vs. S.