FIGURE 2.
SMC2 protein is down-regulated upon WNT signaling inhibition. Ls174T/dnTCF4 (A and B) and Ls174T/pTER-β-catenin (C and D) cell lines were cultured in absence or presence of 5 μg/μl doxycycline (Dox) during the indicated time points. Cells were lysed and analyzed by WB using the indicated antibodies. Representative data from three replicates/independent experiments are shown.