TABLE 1.

Comparison of the distances between residues Thr-394 and Ser-652 in the x-ray structure and smFRET studies

Compound	Distances from average conformation in smFRET	Distances from crystal structure	References
	Å	Å
Glutamate	40.5	29.6	Ref. 20
Chlorowillardiine	42.1	30.3	Ref. 39
Nitrowillardiine	41.7	30.4	Ref. 39
Iodowillardiine	42.8	30.6	Ref. 50
UBP-282	43.9	37.7	Ref. 53