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. 2012 Aug 6;80(4):923–940. doi: 10.3797/scipharm.1206-12

Tab. 5.

Pharmacokinetic parameters of atorvastatin (20 mg) and aspirin (75 mg) (n=6, Mean±SD).

Parameter Atorvastatin Aspirin
Cmax (ng/mL) 11.4 ± 1.57 552 ± 85.3
tmax (h) 2.2 ± 0.70 0.95 ± 0.60
AUC0–t (ng h/mL) 74.1 ± 20.2 1632 ± 148
AUC0–inf (ng h/mL) 76.7 ± 21.5 1655 ± 161
t1/2 (h) 4.1 ± 1.03 3.07 ± 1.99
Ke (h−1) 0.18 ± 0.06 0.31 ± 0.16
Vd (L) 1.55 ± 0.15 0.20 ± 0.12
CL (L/h/kg) 0.28 ± 0.09 0.05 ± 0.00