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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Brain Behav Immun. 2012 Oct 16;27(1):145–154. doi: 10.1016/j.bbi.2012.10.009

Table 5.

Effect of MBI-ld vs. Education Control at Two Months on CRP, IL-6, and Cortisol

Biomarkers Post Mean
for MBI-ld
Groupa 		Post Mean for
Education
Groupa 		MBI-ld − Education
(Effect Estimates)		 Standard
Errors		 Effect Size
in SD
Units		 p-Valueb
CRP 4.70 5.67 −0.97 0.56 −0.23 0.08
IL-6 1.91 1.76 0.15 0.16 0.05 0.36
Cortisol
(mean of noon,
5pm, bed)		 0.11 0.12 −0.01 0.02 −0.07 0.61
a

Estimates of 2-month means based on the multivariate longitudinal modeling.

b

These are double sided p-values uncorrected for multiplicity. The global test of the average effect size across the 3 biomarkers was the first stage of planned testing in a closed testing procedure that strongly controlled Type I error to alpha=0.05. Its p-value was 0.27, which means that no further planned testing was allowed. The p-values reported here are exploratory for decisions about future trials.