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Parallel generation and analysis of iPSCs and OF from common parental fibroblasts. (A) Common parental MEFs. (B) Typical iPSC colonies before picking (boxed). (C) Typical OF colonies before picking (boxed). (D) Typical ROF colonies (boxed) (scale bars=500 μm). iPSCs, induced pluripotent stem cells; OF, oncogenic foci; MEFs, mouse embryonic fibroblasts; ROF, reprogrammed oncogenic foci.
