Table 3.

Kynurenic acid levels and activity of KAT I and KAT II in the frontal cortex and cerebellum of 3 patients with bronchopneumonia.

Brain region	KYNA	KAT I	KAT II
Frontal cortex expressed in %	13.383 ± 2.290 (383% of CO)**	3.603 ± 1.226 (877% of CO)**	0.511 ± 0.028 (101% of CO)
Cerebellum expressed in %	2.117 ± 0.005 (76% of CO)	1.371 ± 0.680 (479% of CO)*	0.513 ± 0.168 (127% of CO)

Notes: Values represent the mean ± SEM. Significance:

^*P < 0.05;

^**P < 0.01 compared with control (CO).

Values of CO parameters in the frontal cortex (n = 16) and cerebellum (n = 16) for KYNA were 3.49 ± 0.55 and 2.77 ± 0.63 (pmol/mg protein), respectively; for KAT I were 0.41 ± 0.04 and 0.29 ± 0.03 (pmol/mg protein/h), respectively; for KAT II were 0.51 ± 0.06 and 0.40 ± 0.06 (pmol/mg protein/h), respectively.