Table 2. Fractal dimension values of the four regions of interest on cone beam CT images of patients in the study.

ROI	Patients with BP-ONJ	Controls	P-value*
	n = 9	n = 27
	Mean ± standard deviation	Mean ± standard deviation
ROI-1	1.673 ± 0.046	1.678 ± 0.034	0.81
ROI-2	1.653 ± 0.052	1.657 ± 0.040	0.78
ROI-3	1.684 ± 0.048	1.661 ± 0.048	0.17
ROI-4	1.698 ± 0.025	1.670 ± 0.046	0.03

*Generalized estimating equations with robust standard errors

BP-ONJ, bisphosphonates-associated osteonecrosis of the jaws; ROI, region of interest; ROI-1, cancellous bone in the area below the mandibular foramen, in the sagittal plane; ROI-2, cancellous bone in the area above the mandibular foramen, in oblique cut, in the axial plane; ROI-3, cancellous bone anterior to the mental foramen, in the sagittal plane; ROI-4, cancellous bone above the mandibular canal in the axial plane