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. Author manuscript; available in PMC: 2012 Dec 21.
Published in final edited form as: Nat Methods. 2012 Mar 11;9(4):367–372. doi: 10.1038/nmeth.1925

Figure 2.

Figure 2

Sequence identification by hybridization. Three different hairpins (marked as molecule 1, 2, 3) were identified by two different oligos (marked as oligo1 and 2) (see Methods). Left panel: Experimental traces recorded during hairpin open-close cycles. To show the corresponding blockage, oligos 1 and 2 were added sequentially into the solution: oligo 1 hybridized on molecules 2 and 3, while oligo 2 hybridized on molecules 1 and 2. Right panel: Histogram of blockages from oligos 1 (orange) and 2 (blue) on each molecule, while the full extension of the molecule is shaded in grey.