Table 4.

A wide variety of equipment exists at various BSL-4 laboratories for performance of sophisticated methods.

Type of equipment	Example of equipment used
General Laboratory equipment	Class II and III biosafety cabinets Temperature-controlled, humidified CO2 cell culture incubators of all types Refrigerators (2–8 °C), Freezers (−20 to −80 °C), Liquid Nitrogen storage Ultra-, super speed, table top and microfuge centrifuges Plate readers of various types, standard or specialized Plate washers Microwave Tissue grinders Water baths, if approved for use Chemical balances Autoclaves
Specialized immunoassay equipment	Sector® Imager 6000 (Meso Scale Discovery) Virocyt 2100 Virus Counter (Applikon Biotechnology) Flow cytometers, e.g., Fortessa (BD Biosciences) ELISPOT readers and bead/cell sorters
Animal treatment or handling equipment	Telemetry, e.g., DSI JETTM (Data Sciences International) Aerosol exposure systems, e.g., AeroMP (Biaera Technologies) Animal weigh scales (large and small)
Clinical chemistry and pathology instruments	Serum chemistry machines such as Vitros® (Ortho Clinical Dignostics) Hematology machines, such as Advia® 120 (Siemens Healthcare Diagnostics) Coagulation machines, e.g., Sysmex CA-560 (Sysmex) Histology scanners Tissue digesters
Imaging instruments	Light boxes/digital camera setups Microscopes, such as inverted, fluorescence, or dissecting scopes, Luminex 100/200TM (Luminex Corp.) Plethysmography equipment (Buxco Research Systems) Imaging equipment, such as MRI, PET/CT, Ultrasound, X-ray fluoroscopy, SPECT/CT High content imaging, e.g., (PerkinElmer)