Figure 6.

Histological depiction of in vivo targeting in atherosclerosis. A) Representative VCAM-1 staining on the aorta of control mice, where only autofluorescence signals were detected. B) Higher-magnification view of the boxed area in panel A. C) Representative VCAM-1 staining (green) in the aorta of ApoE^−/− mice (FITC-labeled secondary antibody). Green signal in the lumen of the aorta demonstrates strong VCAM-1 expression. D) Higher-magnification view of the boxed area in panel C. Blue represents DAPI nuclear staining.