Table 1.

Blood leukocyte composition is affected in macrophage- and granulocyte-specific GRK2 deficiency

Population	WT	LysM-Cre GRK2 flox/flox
T cells	20.2 ± 1.3	18.6 ± 0.9
CD4+ T cells	67.9 ± 0.5	69.4 ± 0.6
CD8+ T cells	25.7 ± 0.6	24.7 ± 0.2
B cells	22.1 ± 2	31 ± 1.3*
Granulocytes	29.4 ± 2	24.5 ± 0.8*
Monocytes	16.1 ± 1.6	15.8 ± 0.5
Ly6Chigh monocytes	56.5 ± 1.3	46.2 ± 1.2*
Ly6Clow monocytes	33.8 ± 1.9	44.2 ± 0.9*

Leukocyte populations were determined in the blood from WT and LysM-Cre GRK2^flox/flox chimeras. Numbers shown are the relative percentages of living cells, except for CD4 and CD8 (% of CD3e⁺ cells) and Ly6C^high/Ly6C^low monocytes (% of monocytes).

^*P < 0.05 vs. WT.