Decreased glycogen accumulation following β-2-agonist administration. Periodic-acid Schiff staining for glycogen in paraffin-embedded sections of the cerebellum (A–D), hippocampus (E–H), and quadriceps (I–L). Original view: ×400. Two sections were examined for each group; representative images are shown. GAA-KO mice were untreated (A, E, I); or were treated with vector alone (B, F, J), vector plus albuterol (C, G, K), or vector plus clenbuterol (D, H, L). Glycogen accumulations in the brain of untreated mice are indicated (arrows).