Table 4.
Clinical and echocardiographic characteristics of different LV geometrical patterns
|
Clinical and echocardiographic variables (±SD) |
Left ventricular geometrical patterns |
p value |
|||
|---|---|---|---|---|---|
| Normal | Concentric remodelling | Concentric hypertrophy | Eccentric hypertrophy | ||
| Age (years) |
57.62 ± 9.93 |
57.53 ± 9.99 |
61.19 ± 11.79 |
68.44 ± 10.25 |
<0.001 |
| Male [n (%)] |
36 (42.9) |
12 (14.3) |
16 (19.0) |
20 (23.8) |
0.003 |
| Female [n(%)] |
32 (22.4) |
33 (23.1) |
48 (33.4) |
30 (21.0) |
|
| Age at diagnosis (years) |
54.85 ± 10.09 |
54.02 ± 8.84 |
55.17 ± 12.33 |
55.88 ± 11.13 |
0.865 |
| BMI (kg/m2) |
25.97 ± 4.250 |
27.20 ± 4.99 |
29.72 ±6.01 |
27.60 ±5.206 |
0.001 |
| BSA (m2) |
1.74 ± 0.17 |
1.74 ± 0.15 |
1.78 ± 0.19 |
1.74 ± 0.15 |
0.581 |
| DBP (mmHg) |
94.71 ± 10.14 |
98.67 ± 1.40 |
100.62 ± 10.97 |
95.20 ± 7.62 |
0.003 |
| SBP (mmHg) |
150.59 ± 14.24 |
166.67 ± 16.65 |
169.69 ± 20.39 |
159.60 ± 18.40 |
<0.001 |
| MAP (mmHg) |
113.33 ± 8.43 |
121.33 ± 11.53 |
123.65 ± 12.83 |
116.67 ± 10.034 |
<0.001 |
| HTN duration (years) |
2.76 ± 4.33 |
3.51 ± 3.32 |
6.02 ± 4.37 |
12.56 ± 8.41 |
<0.001 |
| IVSWTd (cm) |
0.96 ± 0.13 |
1.05 ± 0.11 |
1.59 ± 0.21 |
1.18 ± 0.14 |
<0.001 |
| LVPWTd (cm) |
0.87 ± 0.08 |
1.02 ± 0.10 |
1.47 ± 0.16 |
0.98 ± 0.098 |
<0.001 |
| LVIDd (cm) |
4.76 ± 0.29 |
4.35 ± 0.21 |
4.90 ± 0.34 |
5.41 ± 0.30 |
<0.001 |
| LVIDs (cm) |
3.23 ± 0.39 |
2.98 ± 0.27 |
3.36 ± 0.41 |
3.96 ± 0.38 |
<0.001 |
| FS |
32.53 ± 5.30 |
31.53 ± 4.92 |
31.72 ± 5.71 |
26.96 ± 4.27 |
<0.001 |
| RWT (cm) |
0.37 ± 0.04 |
0.47 ± 0.04 |
0.60 ± 0.08 |
0.36 ± 0.031 |
<0.001 |
| LV mass (g) |
150.00 ± 25.39 |
153.20 ± 19.71 |
326.12 ± 74.14 |
232.32 ± 25.38 |
<0.001 |
| LVMI-BSA (g/m2) |
86.59 ± 14.80 |
88.56 ± 11.22 |
187.22 ± 51.72 |
134.48 ± 25.84 |
<0.001 |
| LVMI-height2.7 (g/m2.7) | 40.32 ± 7.97 | 42.47 ± 5.41 | 94.47 ± 25.66 | 65.52 ± 13.37 | <0.001 |
HTN=hypertension, BMI=Body Mass Index, BSA=Body surface area, DBP=Diastolic blood pressure, SBP=Systolic blood pressure, MAP=Mean arterial pressure, IVSWTd=Interventricular septal wall thickness at end-diastole, LVPWTd=LV posterior left ventricular wall at end-diastole, LVIDd=LV internal diameter at end-diastole, LVIDs=LV internal diameter at end-systole, FS=fractional shortening, RWT=Relative wall thickness , LVMI-BSA=Left Ventricular mass indexed to Body Surface Area, LVMI-height 2.7=left ventricular mass indexed to height 2.7.