Table 4.
FBAT analysis ofSLC25A27in Japanese family samples
| Marker | Location | Allelea | Familiesb | Frequency | Z-scorec | Pvalued |
|---|---|---|---|---|---|---|
| rs12192544 |
5’ |
C |
68 |
0.888 |
0.000 |
1.000 |
| |
|
G |
|
0.112 |
0.000 |
|
| rs9381469 |
Intron 3 |
G |
138 |
0.532 |
0.147 |
0.883 |
| |
|
A |
|
0.468 |
−0.147 |
|
| rs6901132 |
Intron 4 |
A |
132 |
0.573 |
0.899 |
0.368 |
| |
|
G |
|
0.427 |
−0.899 |
|
| rs6901178 |
Intron 4 |
G |
61 |
0.896 |
−1.990 |
0.046 |
| |
|
A |
|
0.104 |
1.990 |
|
| rs2270450 |
Exon 9 UTR |
C |
109 |
0.771 |
0.877 |
0.380 |
| |
|
T |
|
0.229 |
−0.877 |
|
| P value after multimarker testing | 0.073 | |||||
aMajor allele is listed first; bNumber of informative families used by FBAT; cPositive score indicates the risk allele, negative score indicates the protective allele; dP <0.05, additive model, significant P values are indicated in bold italics; UTR, Untranslated region.