Table 2.
Over-represented KEGG pathways in the ILmPFC, 24h post stress according to DAVID
| KEGG pathway | pvalue* | Fold Enrichment | Benjamini | FDR | Genes |
|---|---|---|---|---|---|
| Neurotrophin signaling pathway (04722) |
<0.001 |
6.239 |
0.006 |
0.078 |
BRAF, RGD1306565, CAMK2G, PTPN11, NTRK3, MAP3K5, GSK3B, NTRK2, PIK3CA, LOC685605, CAMK2A, LOC685653, LOC685626, LOC685590 |
| ErbB signaling pathway (04012) |
0.003 |
6.165 |
0.101 |
2.694 |
CBLB, BRAF, GSK3B, CAMK2G, PIK3CA, LOC685605, CAMK2A, LOC685626, LOC685653, LOC685590 |
| Long-term potentiation (04720) |
0.007 |
6.518 |
0.169 |
6.868 |
GRIN2B, BRAF, CAMK2G, GRIN2A, CAMK2A |
| Axon guidance (04360) |
0.014 |
4.126 |
0.252 |
13.797 |
EPHA5, SEMA6A, NRP1, PLXNA2, GSK3B, UNC5C |
| Cell adhesion molecules (04514) |
0.025 |
3.541 |
0.346 |
23.766 |
GLG1, NCAM1, ALCAM, NLGN2, NEO1, NEGR1 |
| Amyotrophic lateral sclerosis (05014) |
0.028 |
5.922 |
0.332 |
26.567 |
SLC1A2, MAP3K5, RGD1306565, GRIN2B, GRIN2A |
| Glioma (05214) |
0.031 |
5.727 |
0.314 |
28.605 |
BRAF, CAMK2G, PIK3CA, LOC685605, CAMK2A, LOC685626, LOC685653, LOC685590 |
| Phosphatidylinositol signaling system (04070) | 0.044 | 4.991 | 0.375 | 38.162 | SYNJ1, PIK3CA, LOC685605, LOC497978, LOC685626, LOC685653, PIP4K2B, LOC685590 |
* = p < 0.05 FDR = false discovery rate.