Table 1.

Patient (n – 141) Characteristics and Univariate Analysis for Impact on Local Control

Characteristic	# of Patients (range or %)	p value
Mean Age (yrs) at end of radiation	67 (33–94)	0.9055
Gender		0.3902
male	125 (88.7%)
female	16 (11.3%)
Race		0.1133
Caucasian	119 (84.4%)
Non-caucasian	22 (15.6%)
Median Pack Years	44 (0–135)	0.6769
Smoker		0.3530
Never	12 (8.5%)
Former	92 (65.2%)
Current	32 (22.7%)	0.5568
Unknown	5 (3.5%)
Heavy Alchohol Use		0.0630
Never (Reference)	89 (63.1%)
Former	21 (14.9%)	0.8836
Current	19 (13.5%)	0.0222
Unknown	12 (8.5%)
Ant Commissure		0.0505
Involved	71 (50.3%)
Non Involved	52 (36.9%)
Unknown	18 (12.8%)
Tumor Bulk		0.6386
Bulky	55 ( 39%)
Non bulky	86 ( 61%)
Hemoglobin (g/dL)	14.2
Grade		0.6614
Well (Reference)	43 (30.5%)
Moderate	57 (40.4%)	0.7192
Poor	14 (10%)	0.3646
Unknown	27 (19.1%)
Stage (T2b vs T1a/b/2a)		0.0205
1a	65 ( 46%)	0.0033
1b	21 (14.9%)	0.1766
2a	29 (20.6%)	0.0621
2b (Reference)	25 (17.7%)
Unknown	1 (1%)
Subglottic Ext		0.0505
Yes	18 (12.8%)
No	96 (68.1%)
Missing	27 (19.2%)
Supraglottic Ext		0.4668
Yes	30 (21.2%)
No	87 (61.7%)
Missing	24 (17%)
Median Overall Treatment Time (wks)	6.5 (4–9.7)
Radiation Dose (cGy) as Continous	6820 (6300–7264)	0.0367
≤66 Gy	45
> 66 Gy	96
Median Dose/Fraction	212 (176–256)	0.1353
≤2Gy/fx	45 (31.9%)
>2Gy/fx	95 (67.4%)
missing	1 (1%)
Mean Follow-Up (month)	67.7 (0–239)