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. 2012 Dec 21;7(12):e52399. doi: 10.1371/journal.pone.0052399

Table 6. Selected substances and signals differing between categories of ethnic background at visits V1 through V3.

Median concentration (IQR) [mM/mM Creatinine] ANOVA
Visit Compound West South Asia All Others p-value
V1 Formate 0.03 (0.024–0.04) 0.04 (0.028–0.059) 0.043 (0.029–0.061) 2e-9
Alanine 0.034 (0.027–0.047) 0.045 (0.032–0.065) 0.044 (0.031–0.058) 5e-8
3-Hydroxyisovalerate 0.008 (0.0062–0.011) 0.01 (0.0075–0.013) 0.01 (0.0079–0.013) 2e-8
1,6-Anhydroglucose 0.0035 (0.002–0.009) 0.003 (0.002–0.006) 0.002 (0.001–0.004) 6e-8
Lactate/Threoninex 25 (17–34) 34 (23–57) 36 (23–55) 4e-12
Unknown multiplet, 0.55 ppmx 2.1 (1.8–2.5) 2.4 (1.9–3.1) 2.5 (2–3.1) 7e-9
V2 Formate 0.043 (0.034–0.058) 0.061 (0.042–0.08) 0.066 (0.046–0.094) 1e-20
Alanine 0.059 (0.042–0.08) 0.073 (0.051–0.093) 0.069 (0.047–0.1) 1e-5
3-Hydroxyisovalerate 0.0094 (0.008–0.012) 0.012 (0.01–0.016) 0.012 (0.01–0.015) 3e-12
1,6-Anhydroglucose 0.006 (0.0032–0.012) 0.004 (0.002–0.007) 0.004 (0.002–0.007) 8e-6
Lactate/Threoninex 49 (36–70) 64 (42–90) 62 (43–93) 3e-6
Unknown multiplet, 0.55 ppmx 4.5 (3.9–5.4) 5.4 (4.3–6.4) 5.3 (4.4–6.6) 5e-10
V3 Formate 0.013 (0.0093–0.019) 0.02 (0.014–0.029) 0.02 (0.013–0.029) 2e-11
Alanine 0.016 (0.013–0.023) 0.024 (0.019–0.031) 0.022 (0.017–0.031) 8e-14
3-Hydroxyisovalerate 0.0048 (0.003–0.007) 0.006 (0.004–0.008) 0.006 (0.004–0.008) 3e-6
1,6-Anhydroglucose 0.0041 (0.0017–0.01) 0.003 (0.001–0.006) 0.003 (0.001–0.005) 2e-6
Lactate/Threoninex 6.9 (4.7–11) 9.8 (7.3–14) 11 (7.1–15) 5e-11
Unknown multiplet, 0.55 ppmx 1.5 (1.2–2) 1.9 (1.4–2.3) 1.8 (1.4–2.3) 5e-4
x

Concentrations of the unidentified signal and the combined lactate and threonine variable in arbitrary units, but nonetheless normalized to creatinine.