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. 2012 Dec 21;7(12):e52284. doi: 10.1371/journal.pone.0052284

Table 1. Literature review of computational simulations of CSF motion in the cervical SSS and/or craniospinal junction in healthy conditions and patients with craniospinal disorders.

Author Technique Geometry Tissue motion Arachnoid trabeculae Nerve roots
Gupta et al. [15] CFD, anisotropic porous media 3D subject-specific No Yes No
Stockman et al. [20] CFD, Lattice Boltzmann 2D idealized No Yes Yes
Roldan et al. [21] 3D rigid wall CFD 3D subject-specific No No No
Linge et al. [22] 3D rigid wall CFD 3D idealized No No No
Loth et al. [14] 3D rigid wall CFD 2D concentric ellipse based on subject No No No
Rutkowska et al. [23] 3D rigid wall CFD 3D patient specific No No No
Bertram [30] Numerical model/wave propagation 2D idealized axisymmetric, tapered tubes Yes No No
Cirovic [28] Numerical model/wave propagation 2D concentric tube with constant diameter Yes No No
Carpenter et al. [48],Elliott et al. [49],Cirovic et al. [50] Numerical model/wave propagation 1D coaxial, fluid-filled, elastic tubes Yes No No
Elliott et al. [51] Two multiple-compartment hydraulic circuit models 1D coaxial, fluid-filled, permeable tubes No No No
Linninger et al. [52] FSI Multi compartment model of intracranial dynamics Yes No No
Bilston et al. [53] CFD 2D Axisymmetric, cylindrical model Yes No No

Abbreviations: CSF = cerebrospinal fluid, SSS = spinal subarachnoid space, CFD = computational fluid dynamics, FSI = fluid-structure interaction.