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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Mol Cancer Res. 2012 Oct 10;10(12):1567–1579. doi: 10.1158/1541-7786.MCR-12-0209-T

Figure 1. Effect of oxaliplatin and hyperthermia on Mapa-induced cytotoxicity in CX-1 cells.

Figure 1

(A) CX-1 cells were treated with oxaliplatin for 20 h and exposed to normothermic or hyperthermic (42°C) conditions for 1 h in the presence/absence of Mapa and oxaliplatin and then incubated for 3 h at 37°C in the presence/absence of Mapa and oxaliplatin. Morphological features were analyzed with a phase-contrast microscope. (B, C) Survival was analyzed by the trypan blue dye exclusion assay (B) or colony formation assay (C). Error bars represent SD from triplicate experiments. (D) Proliferation assay was performed at day 0–4 after indicated treatment.