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. Author manuscript; available in PMC: 2013 Dec 21.
Published in final edited form as: ACS Chem Biol. 2012 Sep 14;7(12):1975–1983. doi: 10.1021/cb300392z

Figure 2. Ligand-induced ERK phosphorylation in WT S1P3 Jump-In stable cell lines (Mean ± SEM; n=3), revealing CYM-5541 is a full agonist of S1P3.

Figure 2

Targetable Jump-In™ TI™ CHO-K cell lines were used to integrate a single copy of S1P3 in a site-specific manner. WT Jump-In stable cell lines were stimulated with increasing concentrations of either S1P or CYM-5541.