Table 2.
Incidence of major complications and mortality with time
| Complication | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | Coefficient | p value | Average % change/year |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stroke | 0.31 (0.13, 0.48) |
0.44 (0.23, 0.65) |
0.45 (0.24, 0.66) |
0.29 (0.14, 0.44) |
0.35 (0.18, 0.53) |
0.16 (0.06, 0.27) |
0.28 (0.15, 0.41) |
0.28 (0.15, 0.41) |
0.19 (0.08, 0.30) |
0.23 (0.12, 0.34) |
−0.072 (−0.129, 0.016) |
0.012 | −6.90 |
| Pulmonary compromise | 0.74 (0.47, 1.01) |
1.18 (0.79, 1.57) |
0.88 (0.59, 1.17) |
0.99 (0.71, 1.27) |
0.90 (0.63, 1.17) |
0.92 (0.67, 1.16) |
1.10 (0.84, 1.36) |
0.89 (0.65, 1.13) |
0.97 (0.72, 1.21) |
0.91 (0.69, 1.14) |
0.001 (−0.03, 0.033) |
0.932 | 0.12 |
| Sepsis | 0.22 (0.07, 0.37) |
0.20 (0.06, 0.35) |
0.28 (0.11, 0.44) |
0.15 (0.05, 0.26) |
0.24 (0.1, 0.38) |
0.23 (0.11, 0.35) |
0.31 (0.17, 0.45) |
0.27 (0.14, 0.40) |
0.37 (0.22, 0.52) |
0.12 (0.04, 0.2) |
0.012 (−0.048, 0.072) |
0.695 | 0.95 |
| Shock/cardiopulmonary arrest | 0.24 (0.08, 0.40) |
0.22 (0.08, 0.37) |
0.15 (0.03, 0.28) |
0.12 (0.02, 0.22) |
0.29 (0.14, 0.44) |
0.17 (0.06, 0.27) |
0.15 (0.05, 0.24) |
0.18 (0.07, 0.29) |
0.18 (0.08, 0.29) |
0.22 (0.11, 0.33) |
−0.006 (−0.079, 0.067) |
0.872 | −0.56 |
| Acute myocardial infarction | 0.65 (0.40, 0.91) |
0.72 (0.45, 0.98) |
0.36 (0.18, 0.55) |
0.42 (0.24, 0.6) |
0.53 (0.32, 0.74) |
0.33 (0.19, 0.48) |
0.62 (0.42, 0.82) |
0.54 (0.36, 0.73) |
0.42 (0.26, 0.58) |
0.33 (0.19, 0.46) |
−0.044 (−0.088, < 0.001) |
0.049 | −4.23 |
| Cardiac (except myocardial infarction) | 6.08 (5.33, 6.83) |
6.30 (5.52, 7.09) |
6.24 (5.49, 6.99) |
6.31 (5.63, 7.00) |
6.21 (5.51, 6.90) |
6.60 (5.97, 7.23) |
6.66 (6.03, 7.28) |
6.82 (6.18, 7.46) |
6.58 (5.96, 7.21) |
6.17 (5.59, 6.74) |
0.006 (−0.006, 0.018) |
0.344 | 0.57 |
| Pneumonia | 1.03 (0.71, 1.35) |
1.02 (0.7, 1.33) |
0.81 (0.53, 1.09) |
0.75 (0.51, 0.99) |
0.99 (0.71, 1.28) |
0.79 (0.57, 1.01) |
1.13 (0.87, 1.39) |
1.00 (0.75, 1.26) |
1.10 (0.84, 1.35) |
0.86 (0.64, 1.08) |
0.007 (−0.025, 0.039) |
0.657 | 0.71 |
| Pulmonary embolism | 0.57 (0.33, 0.80) |
0.79 (0.51, 1.07) |
0.78 (0.51, 1.06) |
0.73 (0.49, 0.97) |
0.82 (0.57, 1.08) |
0.72 (0.51, 0.93) |
1.14 (0.87, 1.40) |
0.92 (0.68, 1.16) |
0.67 (0.47, 0.88) |
0.95 (0.71, 1.18) |
0.032 (−0.002, 0.065) |
0.064 | 3.21 |
| Mortality | 0.42 (0.22, 0.63) |
0.43 (0.23, 0.63) |
0.24 (0.09, 0.39) |
0.26 (0.12, 0.41) |
0.42 (0.23, 0.61) |
0.27 (0.14, 0.39) |
0.24 (0.12, 0.36) |
0.19 (0.08, 0.31) |
0.20 (0.08, 0.31) |
0.16 (0.06, 0.25) |
−0.100 (−0.157, 0.042) |
0.001 | −9.79 |
Values are expressed as incidence, with 95% CI in parentheses.