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. 2012 Aug 28;590(Pt 22):5629–5652. doi: 10.1113/jphysiol.2012.239418

Table 1.

Range of parameters used in generating model population with random sampling of parameter space

Parameter Default value Testing range
Rm (kΩ cm2) 11 10–18
Cm (μF cm−2) 1 0.5–1.5
Diameter (μm) 60 40–80
Inline graphic (S cm−2)  — 0.02–0.1
Inline graphic (μS cm−2) 100–500
Inline graphic (μS cm−2) 30–150
V1/2 activation of A channel (mV) −1 −20 to 20
V1/2 inactivation of A channel (mV) −56 −80 to −40
V1/2 activation of T channel (mV) −60 −75 to −35
V1/2 inactivation of T channel (mV) −85 −105 to −65
V1/2 activation of h channels (mV) −82 −100 to −60
Activation time constant of A channel (ms) 0.032 0.02–0.1
Inactivation time constant of A channel (ms) 2 1–5
Activation time constant of T channel (ms) 1.004 1–5
Inactivation time constant of T channel (ms) 31.012 10–50
Activation time constant of h channel (ms) 46.51 25–75
Ca2+ decay time constant (ms) 30 10–90

For each model, each parameter (first column) was drawn independently from a uniform distribution, generated around a large neighbourhood of their default values (second column), within set bounds (third column).