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. 2012 Aug 28;590(Pt 22):5629–5652. doi: 10.1113/jphysiol.2012.239418

Table 3.

Sensitivity analysis for IRD measurements corresponding to various active parameters related to the A-type K+ channel

A-type K+ channel

Effect of increase in Tested range Rin |Z|max
Rm (kΩ cm2) 1–10 Increases Increases
Cm (μF cm−2) 0.5–2 No effect Decreases*
Inline graphic (mS cm−2) 0–0.5 Decreases Decreases
Membrane potential (mV) −150 to 30 Biphasic Biphasic
V1/2 activation of A channel (mV) −150 to 0 Inverted bell Inverted bell
V1/2 inactivation of A channel (mV) −100 to 0 Decreases Decreases
Activation time constant of A channel (ms) 1–30 No effect No effect
Inactivation time constant of A channel (ms) 1–100 No effect No effect

Resonance-related IRD measurements are not shown because A-type K+ channels are not resonating conductances. Associated plots may be found in Figs S6–S8.

*

A very small change.