Table 5.

Comparison of conductance levels (in pS) of GluA1 receptors with and without TARPs

	GluA1 alone
Conductance level	Derkach et al. 1999 10 μm AMPA	Banke et al. 2000† 10 μm glutamate	Fucile et al. 2006 1 μm AMPA	Kristensen et al. 2011 2 mm glutamate	This study 10 mm glutamate	GluA1 + TARP This study 10 mm glutamate
1	8–9**	4	***	4–5**	***	10–12*
2	12–14**	8	11	9	7.6	19–25*
3	19–21**	15	15	14–15**	12.9	37–43*
4	28–30**	25	22	21–25**	24.8	56

Each of the four conductance levels is greater in the presence of TARP, in most cases at least doubling. Although previous work utilised different agonists and agonist concentrations, the four conductance levels detected were still all lower than the highest conductance levels seen when GluA1 was coexpressed with TARPs. *Dependent on which TARP was co-expressed. **Dependent on the phosphorylation state of the receptor. ***Only three conductance levels were observed. †The values from Banke et al. 2000 were calculated as the weighted means of the conductance levels given in their fig. 6 legend.