Figure 7. Plasma levels of noradrenaline (NA) and 3,4-dihydroxyphenylglycol (DHPG), and cardiac content of NA.

Plasma NA was significantly increased and LV NA decreased in 7-month-old R6/1 compared with age-matched wild-type (WT) mice. These changes were not evident at 3 months old. There were no significant changes in plasma DHPG levels between R6/1 and WT mice at 3 or 7 months old. *P < 0.05 vs. age-matched WT and 3-month-old R6/1 mice (two-way ANOVA). n= 4–6 per group.