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. 2012 Dec 3;109(51):21110–21115. doi: 10.1073/pnas.1210804109

Fig. 5.

Fig. 5.

Neuroprotective effect of pineal ALLO is associated with the decrease in caspase-3 activity in Purkinje cells. (A and C) Purkinje cells expressing active caspase-3 in lobes IV (A) and IX (C) of control male quail chicks, Px male quail chicks, and Px plus ALLO male quail chicks at P3, P5, and P7. (B and D) Comparison of the number of Purkinje cells expressing active caspase-3 in lobes IV (B) and IX (D) among control male quail chicks, Px male quail chicks, and Px plus ALLO male quail chicks at P3, P5, and P7 (n = 12). **P < 0.01 vs. control; †P < 0.05 or ††P < 0.01 Px plus ALLO vs. Px. (E) TUNEL-positive Purkinje cells in lobe IV of control male quail chicks, Px male quail chicks, and Px plus ALLO male quail chicks at P3, P5, and P7. (F) Comparison of the number of TUNEL-positive Purkinje cells in lobe IV among control male quail chicks, Px male quail chicks, and Px plus ALLO male quail chicks at P3, P5, and P7 (n = 12). *P < 0.05 vs. control; †P < 0.05 Px plus ALLO vs. Px. Each column and vertical line in B, D, and F represent the mean ± SEM.