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. 2012 Nov 30;109(51):21081–21086. doi: 10.1073/pnas.1219280110

Fig. 4.

Fig. 4.

CTCF or cohesin knockdown results in significant decreases of long-range DNA interactions between HS5-1 and promoters. SK-N-SH cells were infected with shGFP (control), shCTCF, or shRad21 lentivirus, and crosslinking frequencies were measured by 3C. Data are presented as means ± SEM (n = 4). *P < 0.05; **P < 0.01.