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. 2012 Dec 3;109(51):E3558–E3567. doi: 10.1073/pnas.1219203110

Fig. 5.

Fig. 5.

No forward transport of surface TrkB-QDs on nonmigrating cells. (A–C) (Upper) Diagrams illustrate the migratory behavior of the cell at two different times, and red dots depict QDs. (Lower) The trajectories of QDs along the long process of nonmigrating cells during the observation. Red lines represent the average of all trajectories (n = 52, 58, and 67, respectively). (D–F) The distribution of QD movement in the long process of nonmigrating cells in 2-s (green), 12-s (blue), and 72-s (red) intervals. (G) Cumulative percentage plot for the distribution of D values found along the long process of nonmigrating cells. Data points below depict the mean D values for three groups of neurons with different states of the growth cones. No significant difference was found among all curves (P > 0.09, K-S test). (H) The mean value of v (± SEM) along the long process of nonmigrating cells. No significant difference was found (P > 0.14, t test). (I) Percentages of QDs showing drift movements in the forward (blue) and rearward (red) directions along extending, stalling, and retracting processes, respectively. The numbers associated with the bars represent the total number of QDs examined. ***P < 0.001. Error bars indicate SEM.