Whole-brain analysis of reward anticipation and reward feedback. (A) Positive BOLD response (PBR) during reward anticipation and reward feedback (FWE P value < 0.05). The location of the VS (±15, 9, −9; 9-mm radius) is depicted in blue. (B) Whole-brain analysis of the association of RASGRF2 haplotype and BOLD response during reward anticipation. This analysis revealed a significant activation in the precentral gyrus that extended into the anterior cingulate cortex. The figure shows activation in the precentral gyrus (FWE-corrected, P = 0.008; 6, 16, 49; t = 4.37; k = 58) with a subpeak in the anterior cingulate gyrus (−6, −1, 43).