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. 2012 Nov 9;12:386. doi: 10.1186/1472-6963-12-386

Table 5.

Projected direct costs by vaccination strategy for children <10 years old

  Costs with PCV-7 vaccination, US$ Cost savings, US$*
PHiD-CV vs PCV-7 PCV-13 vs PCV-7 PHiD-CV vs PCV-13
Vaccine and vaccine administration cost
156,455,040
0
0
0
IPD cost
1,217,684
−112,966
−137,691
24,726
Pneumonia hospitalizations cost
3,939,050
−104,850
−117,264
12,413
AOM cost
98,833,034
−12,500,997
−3,228,848
−8,272,149
Total direct costs 260,444,808 −11,718,813 −3,483,803 −8,235,010

*Negative numbers represent savings in favor of first comparator.

AOM acute otitis media, IPD invasive pneumococcal disease, PCV-7 7-valent pneumococcal conjugate vaccine, PCV-13 13-valent pneumococcal conjugate vaccine, PHiD-CV pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine.