Fig. 2.

Effects of a oxotremorine-M (oxo-M, 10 μM) and b phenylephrine (Phe, 10 μM) on action potential firing in two neurons induced by 2 s depolarizing current injections (120 pA in a, 160 pA in b). Neuron A: wild-type; neuron B: pre-injected with α1a cDNA. c Plots of the number of action potentials (“spikes”) recorded in 2 s (ordinates) against the amplitude of the depolarizing current injection (abscissae) for the two cells illustrated in a and b. Discharges reverted to control after drug washout