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. 2012 Dec 10;12:587. doi: 10.1186/1471-2407-12-587

Table 3.

Dose limiting toxic effects by dose level

Dose level (mg) n Dose limiting toxicity (n)
300
6
nausea, anorexia (1)
400
3
-
500
3
-
600
11
-
700 2 gastric perforation (2)